Skeletal Muscle–Specific Deletion of Lipoprotein Lipase Enhances Insulin Signaling in Skeletal Muscle but Causes Insulin Resistance in Liver and Other Tissues

OBJECTIVE—Skeletal muscle–specific LPL knockout mouse (SMLPL(−/−)) were created to study the systemic impact of reduced lipoprotein lipid delivery in skeletal muscle on insulin sensitivity, body weight, and composition. RESEARCH DESIGN AND METHODS—Tissue-specific insulin sensitivity was assessed usi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wang, Hong, Knaub, Leslie A., Jensen, Dalan R., Jung, Dae Young, Hong, Eun-Gyoung, Ko, Hwi-Jin, Coates, Alison M., Goldberg, Ira J., de la Houssaye, Becky A., Janssen, Rachel C., McCurdy, Carrie E., Rahman, Shaikh M., Choi, Cheol Soo, Shulman, Gerald I., Kim, Jason K., Friedman, Jacob E., Eckel, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
Assuntos:
Obesity Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606858/
https://ncbi.nlm.nih.gov/pubmed/18952837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1839
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados