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Bleach Activates A Redox-Regulated Chaperone by Oxidative Protein Unfolding

Hypochlorous acid (HOCl), the active ingredient of household bleach, is an effective antimicrobial produced by the mammalian host defense to kill invading microorganisms. Despite the widespread use of HOCl, surprisingly little is known about its mode of action. In this study we demonstrate that low...

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Detalles Bibliográficos
Main Authors: Winter, J., Ilbert, M., Graf, P. C. F., Özcelik, D., Jakob, U.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606091/
https://ncbi.nlm.nih.gov/pubmed/19013278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.09.024
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