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Bleach Activates A Redox-Regulated Chaperone by Oxidative Protein Unfolding

Hypochlorous acid (HOCl), the active ingredient of household bleach, is an effective antimicrobial produced by the mammalian host defense to kill invading microorganisms. Despite the widespread use of HOCl, surprisingly little is known about its mode of action. In this study we demonstrate that low...

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Hlavní autoři: Winter, J., Ilbert, M., Graf, P. C. F., Özcelik, D., Jakob, U.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606091/
https://ncbi.nlm.nih.gov/pubmed/19013278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.09.024
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