Bleach Activates A Redox-Regulated Chaperone by Oxidative Protein Unfolding

Hypochlorous acid (HOCl), the active ingredient of household bleach, is an effective antimicrobial produced by the mammalian host defense to kill invading microorganisms. Despite the widespread use of HOCl, surprisingly little is known about its mode of action. In this study we demonstrate that low...

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Bibliographic Details
Main Authors: Winter, J., Ilbert, M., Graf, P. C. F., Özcelik, D., Jakob, U.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2606091/
https://ncbi.nlm.nih.gov/pubmed/19013278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.09.024
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