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Bleach Activates A Redox-Regulated Chaperone by Oxidative Protein Unfolding
Hypochlorous acid (HOCl), the active ingredient of household bleach, is an effective antimicrobial produced by the mammalian host defense to kill invading microorganisms. Despite the widespread use of HOCl, surprisingly little is known about its mode of action. In this study we demonstrate that low...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2606091/ https://ncbi.nlm.nih.gov/pubmed/19013278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.09.024 |
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