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A positive feedback signal transduction loop determines timing of cerebellar long-term depression

Synaptic activity produces short-lived second messengers that ultimately yield a long-term depression (LTD) of cerebellar Purkinje cells. Here we test the hypothesis that these brief second messenger signals are translated into long-lasting biochemical signals by a positive feedback loop that includ...

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Main Authors: Tanaka, Keiko, Augustine, George J.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605966/
https://ncbi.nlm.nih.gov/pubmed/18760697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.06.026
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