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Breakdown of T cell Tolerance and Autoimmunity in Primary Immunodeficiency - Lessons Learned From Monogenic Disorders in Mice and Men

A key feature of the immune system is the capacity to monitor and control infections from non-self pathogens while maintaining tolerance to self-antigens. Primary Immunodeficiencies (PID) are characterized by an increased susceptibility to infections, often associated with aberrant inflammatory resp...

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Autori principali: Westerberg, Lisa S., Klein, Christoph, Snapper, Scott B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605935/
https://ncbi.nlm.nih.gov/pubmed/18955138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2008.10.004
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