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Insights into the evolutionary origins of clostridial neurotoxins from analysis of the Clostridium botulinum strain A neurotoxin gene cluster

BACKGROUND: Clostridial neurotoxins (CNTs) are the most deadly toxins known and causal agents of botulism and tetanus neuroparalytic diseases. Despite considerable progress in understanding CNT structure and function, the evolutionary origins of CNTs remain a mystery as they are unique to Clostridiu...

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Main Authors: Doxey, Andrew C, Lynch, Michael DJ, Müller, Kirsten M, Meiering, Elizabeth M, McConkey, Brendan J
格式: Artigo
語言:Inglês
出版: BioMed Central 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605760/
https://ncbi.nlm.nih.gov/pubmed/19014598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-316
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