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Switch of transforming growth factorβ function from tumor suppression to stimulation in adenomatous polyposis coli (APC) knocked-down human colon carcinoma cells
TGFβ exerts a potent tumor-suppressive effect in the human colon carcinoma CBS and Moser cells. However, TGFβ can also function as a tumor promoter. The mechanisms underlying the tumor promoting effect of TGFβ is not understood. Both the CBS and Moser cells were found to express mutant (truncated) A...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2605685/ https://ncbi.nlm.nih.gov/pubmed/18774639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.07.010 |
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