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Wnt5A Regulates Expression of Tumor Associated Antigens in Melanoma Via Changes in STAT3 Phosphorylation

There are currently no effective therapies for metastatic melanoma and targeted immunotherapy results in the remission of only a very small percentage of tumors. In this study we demonstrate that the non-canonical Wnt ligand, Wnt5A, can increase melanoma metastasis in vivo while downregulating the e...

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主要な著者: Dissanayake, Samudra K., Olkhanud, Purevdorj B., O’Connell, Michael P., Carter, Arnell, French, Amanda D., Camilli, Tura C., Emeche, Chineye D., Hewitt, Kyle J., Rosenthal, Devin T., Leotlela, Poloko D., Wade, Michael S., Yang, Sherry W., Brant, Larry, Nickoloff, Brian J., Messina, Jane L., Biragyn, Arya, Hoek, Keith S., Taub, Dennis D., Longo, Dan L., Sondak, Vernon K., Hewitt, Stephen M., Weeraratna, Ashani T.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605679/
https://ncbi.nlm.nih.gov/pubmed/19074888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2149
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