Wnt5A Regulates Expression of Tumor Associated Antigens in Melanoma Via Changes in STAT3 Phosphorylation

There are currently no effective therapies for metastatic melanoma and targeted immunotherapy results in the remission of only a very small percentage of tumors. In this study we demonstrate that the non-canonical Wnt ligand, Wnt5A, can increase melanoma metastasis in vivo while downregulating the e...

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Detalhes bibliográficos
Main Authors: Dissanayake, Samudra K., Olkhanud, Purevdorj B., O’Connell, Michael P., Carter, Arnell, French, Amanda D., Camilli, Tura C., Emeche, Chineye D., Hewitt, Kyle J., Rosenthal, Devin T., Leotlela, Poloko D., Wade, Michael S., Yang, Sherry W., Brant, Larry, Nickoloff, Brian J., Messina, Jane L., Biragyn, Arya, Hoek, Keith S., Taub, Dennis D., Longo, Dan L., Sondak, Vernon K., Hewitt, Stephen M., Weeraratna, Ashani T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605679/
https://ncbi.nlm.nih.gov/pubmed/19074888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2149
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