Cytosolic Phospholipase A(2)-α: A Potential Therapeutic Target for Prostate Cancer

PURPOSE: Cytosolic Phospholipase A2-α (cPLA2-α) provides intracellular arachidonic acid to supply both cyclooxygenase and lipoxygenase pathways. We aim to determine the expression and activation of cPLA2-α in prostate cancer (PC) cell line and tissue and the effect of targeting cPLA2-α in-vitro and...

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Bibliografiske detaljer
Main Authors: Patel, Manish I., Singh, Jaskirat, Niknami, Marzieh, Kurek, Caroline, Yao, Mu, Lu, Sasa, Maclean, Fiona, King, Nicholas J.C., Gelb, Michael H., Scott, Kieran F., Russell, Pamela J., Boulas, John, Dong., Qihan
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605658/
https://ncbi.nlm.nih.gov/pubmed/19088022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0566
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