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The Nrf2-ARE Pathway: An Indicator and Modulator of Oxidative Stress in Neurodegeneration
Transcriptional activation of protective genes is mediated by a cis-acting element called the antioxidant responsive element (ARE). The transcription factor Nrf2 (NF-E2-related factor 2) binds to the ARE. Activation of this pathway protects cells from oxidative stress-induced cell death. Increased o...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2605641/ https://ncbi.nlm.nih.gov/pubmed/19076431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1196/annals.1427.036 |
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