Vaccine potential of Pseudomonas aeruginosa O-polysaccharide-toxin A conjugates.

Serologically reactive O-polysaccharide from nine serotypes of Pseudomonas aeruginosa were covalently linked to toxin A via reductive amination, with adipic acid dihydrazide serving as a spacer molecule. The conjugates were composed of toxin A/O-polysaccharide ratios ranging from 1.17:1 to 3:1. All...

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Bibliographische Detailangaben
Hauptverfasser: Cryz, S J, Lang, A B, Sadoff, J C, Germanier, R, Fürer, E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1987
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC260556/
https://ncbi.nlm.nih.gov/pubmed/3110065
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