Vaccine potential of Pseudomonas aeruginosa O-polysaccharide-toxin A conjugates.

Serologically reactive O-polysaccharide from nine serotypes of Pseudomonas aeruginosa were covalently linked to toxin A via reductive amination, with adipic acid dihydrazide serving as a spacer molecule. The conjugates were composed of toxin A/O-polysaccharide ratios ranging from 1.17:1 to 3:1. All...

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Publicado en:	Infect Immun
Autores principales:	Cryz, S J, Lang, A B, Sadoff, J C, Germanier, R, Fürer, E
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1987
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260556/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3110065/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.55.7.1547-1551.1987
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