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Cytotoxicity of Shiga toxin for primary cultures of human colonic and ileal epithelial cells.

Shiga toxin purified from Shigella dysenteriae 1 was cytotoxic to cultured epithelial cells from human colon and ileum. The cytotoxicity, which affected only about 50% of treated cells, was neutralized by rabbit antiserum monospecific for Shiga toxin and mediated by protein synthesis inhibition.

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Moyer, M P, Dixon, P S, Rothman, S W, Brown, J E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1987
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260549/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3570477/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.55.6.1533-1535.1987
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