ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells

BACKGROUND: Aldehyde dehydrogenase isozymes ALDH1A1 and ALDH3A1 are highly expressed in non small cell lung cancer. Neither the mechanisms nor the biologic significance for such over expression have been studied. METHODS: We have employed oligonucleotide microarrays to analyze changes in gene profil...

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Detalhes bibliográficos
Main Authors: Moreb, Jan S, Baker, Henry V, Chang, Lung-Ji, Amaya, Maria, Lopez, M Cecilia, Ostmark, Blanca, Chou, Wayne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605459/
https://ncbi.nlm.nih.gov/pubmed/19025616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-87
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