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Deletion and downregulation of MTAP contribute to the motility of esophageal squamous carcinoma cells

Esophageal squamous cell carcinoma (ESCC) is among the most common malignancies, with a low 5-year overall survival rate. In previous studies, we and others have found that 9p21.3 was the most frequently deleted region in ESCC. The MTAP gene, which is located close to CDKN2A/B in 9p21.3, encodes met...

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Dettagli Bibliografici
Pubblicato in:Onco Targets Ther
Autori principali: Cheng, Xiao-Yu, Liu, Zou, Shang, Li, Cai, Hong-Qing, Zhang, Yu, Cai, Yan, Xu, Xin, Hao, Jia-Jie, Wang, Ming-Rong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729838/
https://ncbi.nlm.nih.gov/pubmed/29270023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S151953
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