Alternative methods to analyse the impact of HIV mutations on virological response to antiviral therapy

BACKGROUND: Principal component analysis (PCA) and partial least square (PLS) regression may be useful to summarize the HIV genotypic information. Without pre-selection each mutation presented in at least one patient is considered with a different weight. We compared these two strategies with the co...

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Detalhes bibliográficos
Main Authors: Wittkop, Linda, Commenges, Daniel, Pellegrin, Isabelle, Breilh, Dominique, Neau, Didier, Lacoste, Denis, Pellegrin, Jean-Luc, Chêne, Geneviève, Dabis, François, Thiébaut, Rodolphe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605450/
https://ncbi.nlm.nih.gov/pubmed/18945369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-8-68
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