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Estimation of dynamical model parameters taking into account undetectable marker values

BACKGROUND: Mathematical models are widely used for studying the dynamic of infectious agents such as hepatitis C virus (HCV). Most often, model parameters are estimated using standard least-square procedures for each individual. Hierarchical models have been proposed in such applications. However,...

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Detalhes bibliográficos
Main Authors: Thiébaut, Rodolphe, Guedj, Jérémie, Jacqmin-Gadda, Hélène, Chêne, Geneviève, Trimoulet, Pascale, Neau, Didier, Commenges, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559636/
https://ncbi.nlm.nih.gov/pubmed/16879756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2288-6-38
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