Modification of carbonic anhydrase II with acetaldehyde, the first metabolite of ethanol, leads to decreased enzyme activity

BACKGROUND: Acetaldehyde, the first metabolite of ethanol, can generate covalent modifications of proteins and cellular constituents. However, functional consequences of such modification remain poorly defined. In the present study, we examined acetaldehyde reaction with human carbonic anhydrase (CA...

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主要な著者: Bootorabi, Fatemeh, Jänis, Janne, Valjakka, Jarkko, Isoniemi, Sari, Vainiotalo, Pirjo, Vullo, Daniela, Supuran, Claudiu T, Waheed, Abdul, Sly, William S, Niemelä, Onni, Parkkila, Seppo
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2008
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605449/
https://ncbi.nlm.nih.gov/pubmed/19036170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-9-32
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