Modification of carbonic anhydrase II with acetaldehyde, the first metabolite of ethanol, leads to decreased enzyme activity

BACKGROUND: Acetaldehyde, the first metabolite of ethanol, can generate covalent modifications of proteins and cellular constituents. However, functional consequences of such modification remain poorly defined. In the present study, we examined acetaldehyde reaction with human carbonic anhydrase (CA...

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Detaylı Bibliyografya
Asıl Yazarlar: Bootorabi, Fatemeh, Jänis, Janne, Valjakka, Jarkko, Isoniemi, Sari, Vainiotalo, Pirjo, Vullo, Daniela, Supuran, Claudiu T, Waheed, Abdul, Sly, William S, Niemelä, Onni, Parkkila, Seppo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2008
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605449/
https://ncbi.nlm.nih.gov/pubmed/19036170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-9-32
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