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Chemical control of protein stability and function in living animals

Conditional control of protein function in vivo offers tremendous potential for deconvoluting the roles of individual proteins in complex systems. We recently developed a method in which a small protein domain termed a destabilizing domain confers instability to fusion protein partners in cultured c...

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Detalhes bibliográficos
Main Authors: Banaszynski, Laura A., Sellmyer, Mark A., Contag, Christopher H., Wandless, Thomas J., Thorne, Steve H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605277/
https://ncbi.nlm.nih.gov/pubmed/18836461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1754
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