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Gap Junction Mediated Intercellular Metabolite Transfer in the Cochlea Is Compromised in Connexin30 Null Mice

Connexin26 (Cx26) and connexin30 (Cx30) are two major protein subunits that co-assemble to form gap junctions (GJs) in the cochlea. Mutations in either one of them are the major cause of non-syndromic prelingual deafness in humans. Because the mechanisms of cochlear pathogenesis caused by Cx mutatio...

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Hlavní autoři: Chang, Qing, Tang, Wenxue, Ahmad, Shoeb, Zhou, Binfei, Lin, Xi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605248/
https://ncbi.nlm.nih.gov/pubmed/19116647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004088
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