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Peroxynitrite-dependent activation of protein phosphatase type 2A mediates microvascular endothelial barrier dysfunction

AIMS: We investigated the mechanism by which proinflammatory stimulation induces microvascular endothelial barrier dysfunction. Since protein phosphatase type 2A (PP2A) can mediate paracellular leak and can be inactivated by tyrosine phosphorylation in its catalytic subunit (PP2Ac), we hypothesized...

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Bibliografiske detaljer
Main Authors: Wu, Feng, Wilson, John X.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605194/
https://ncbi.nlm.nih.gov/pubmed/18791203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvn246
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