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Recurrent Intrathecal Methotrexate Induced Neurotoxicity in an Adolescent with Acute Lymphoblastic Leukemia: Serial Clinical and Radiologic Findings

Systemic and intrathecal methotrexate (MTX) are integral components of acute lymphoblastic leukemia (ALL) therapy, but can be associated with neurotoxicity. We describe here the case of an adolescent male with T-cell ALL who developed recurrent episodes of subacute neurotoxicity characterized by slu...

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Detalhes bibliográficos
Main Authors: Brugnoletti, Fulvia, Morris, E. Brannon, Laningham, Fred H., Patay, Zoltán, Pauley, Jennifer L, Pui, Ching-Hon, Jeha, Sima, Inaba, Hiroto
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605174/
https://ncbi.nlm.nih.gov/pubmed/18831032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.21764
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