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Harnessing endogenous miRNAs to control virus tissue tropism as a strategy for developing attenuated virus vaccines

Live, attenuated vaccines remain the safest, most cost-effective intervention against viral infections. Because live vaccine strains are generated empirically and the basis for attenuation is usually ill defined, many important viruses lack an efficient live vaccine. Here, we present a general strat...

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Bibliografiska uppgifter
Huvudupphovsmän: Barnes, Dwight, Kunitomi, Mark, Vignuzzi, Marco, Saksela, Kalle, Andino, Raul
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605097/
https://ncbi.nlm.nih.gov/pubmed/18779050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.08.003
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