Structural requirements of muramylpeptides for induction of necrosis at sites primed with Mycobacterium tuberculosis in guinea pigs.

Intracutaneous injection of N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) in guinea pigs caused an extensive necrotic reaction in footpads prepared by injection of heat-killed Mycobacterium tuberculosis in water-in-mineral-oil emulsion. We examined a variety of analogs and derivatives of muramylpept...

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Detalhes bibliográficos
Main Authors: Nagao, S, Takada, H, Yagawa, K, Kutsukake, H, Shiba, T, Kusumoto, S, Kawata, S, Hasegawa, A, Kiso, M, Azuma, I
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC260502/
https://ncbi.nlm.nih.gov/pubmed/3106217
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