Granuloma formation by muramyl dipeptide associated with branched fatty acids, a structure probably essential for tubercle formation by Mycobacterium tuberculosis.

Muramyl dipeptide, which does not induce epithelioid granuloma when injected alone dissolved in phosphate-buffered saline, could induce extensive granulomas in guinea pigs when chemically conjugated with branched, but not linear, fatty acids. Peptidoglycan fragments of Staphylococcus epidermidis cou...

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Bibliographic Details
Main Authors: Emori, K, Nagao, S, Shigematsu, N, Kotani, S, Tsujimoto, M, Shiba, T, Kusumoto, S, Tanaka, A
Format: Artigo
Language:Inglês
Published: 1985
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC262085/
https://ncbi.nlm.nih.gov/pubmed/3924828
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