Granuloma formation by muramyl dipeptide associated with branched fatty acids, a structure probably essential for tubercle formation by Mycobacterium tuberculosis.

Muramyl dipeptide, which does not induce epithelioid granuloma when injected alone dissolved in phosphate-buffered saline, could induce extensive granulomas in guinea pigs when chemically conjugated with branched, but not linear, fatty acids. Peptidoglycan fragments of Staphylococcus epidermidis cou...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Emori, K, Nagao, S, Shigematsu, N, Kotani, S, Tsujimoto, M, Shiba, T, Kusumoto, S, Tanaka, A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1985
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262085/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3924828/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.49.1.244-249.1985
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