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Prolyl hydroxylase inhibition during hyperoxia prevents oxygen-induced retinopathy
Oxygen-induced retinopathy (OIR) in the mouse, like the analogous human disease retinopathy of prematurity, is an ischemic retinopathy dependent on oxygen-induced vascular obliteration. We tested the hypothesis that chemically overriding the oxygen-induced downregulation of hypoxia-inducible factor...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2604934/ https://ncbi.nlm.nih.gov/pubmed/19057008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805817105 |
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