Rac1 promotes intestinal epithelial restitution by increasing Ca(2+) influx through interaction with phospholipase C-γ1 after wounding

Intestinal mucosal restitution occurs as a consequence of epithelial cell migration and reseals superficial wounds after injury. This rapid reepithelialization is mediated in part by a phospholipase C-γ1 (PLC-γ1)-induced Ca(2+) signaling, but the exact mechanism underlying such signaling and its reg...

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Autors principals: Rao, Jaladanki N., Liu, Stephen V., Zou, Tongtong, Liu, Lan, Xiao, Lan, Zhang, Xian, Bellavance, Emily, Yuan, Jason X.-J., Wang, Jian-Ying
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2008
Matèries:
Translational Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603560/
https://ncbi.nlm.nih.gov/pubmed/18923057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00232.2008
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