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Bax signaling regulates palmitate-mediated apoptosis in C(2)C(12) myotubes

Insulin resistance is a primary characteristic of type 2 diabetes. Several lines of evidence suggest that accumulation of free fatty acids in skeletal muscle may at least in part contribute to insulin resistance and may be linked to mitochondrial dysfunction, leading to apoptosis. Palmitate treatmen...

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Main Authors: Peterson, Jonathan M., Wang, Yan, Bryner, Randall W., Williamson, David L., Alway, Stephen E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Physiological Society 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603553/
https://ncbi.nlm.nih.gov/pubmed/18840766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00738.2007
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