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Bax signaling regulates palmitate-mediated apoptosis in C(2)C(12) myotubes

Insulin resistance is a primary characteristic of type 2 diabetes. Several lines of evidence suggest that accumulation of free fatty acids in skeletal muscle may at least in part contribute to insulin resistance and may be linked to mitochondrial dysfunction, leading to apoptosis. Palmitate treatmen...

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Detalhes bibliográficos
Main Authors: Peterson, Jonathan M., Wang, Yan, Bryner, Randall W., Williamson, David L., Alway, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603553/
https://ncbi.nlm.nih.gov/pubmed/18840766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00738.2007
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