Coplanar polychlorinated biphenyl-induced CYP1A1 is regulated through caveolae signaling in vascular endothelial cells

Polychlorinated biphenyls (PCBs) are persistent environmental contaminants that can induce inflammatory processes in the vascular endothelium. We hypothesize that the plasma membrane microdomains called caveolae are critical in endothelial activation and toxicity induced by PCBs. Caveolae are partic...

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Autores principales: Lim, Eun Jin, Májková, Zuzana, Xu, Shifen, Bachas, Leonidas, Arzuaga, Xabier, Smart, Eric, Tseng, Michael T., Toborek, Michal, Hennig, Bernhard
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603293/
https://ncbi.nlm.nih.gov/pubmed/18786521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2008.08.007
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