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Hydration Profiles of Amyloidogenic Molecular Structures

Hydration shells of normal proteins display regions of highly structured water as well as patches of less structured bulk-like water. Recent studies suggest that isomers with larger surface densities of patches of bulk-like water have an increased propensity to aggregate. These aggregates are toxic...

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Detalhes bibliográficos
Main Authors: Despa, Florin, Fernández, Ariel, Scott, L. Ridgway, Berry, R. Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603265/
https://ncbi.nlm.nih.gov/pubmed/19669515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-008-9122-z
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