Loading...
Backrub-like backbone simulation recapitulates natural protein conformational variability and improves mutant side-chain prediction
Incorporation of effective backbone sampling into protein simulation and design is an important step in increasing the accuracy of computational protein modeling. Recent analysis of high-resolution crystal structures has suggested a new model, termed backrub, to describe localized, hinge-like altern...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2603262/ https://ncbi.nlm.nih.gov/pubmed/18547585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.05.023 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|