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Assembly of the translocase motor onto the preprotein-conducting channel

Bacterial protein secretion is catalyzed by the SecYEG protein-conducting channel complexed with the SecA ATPase motor. To gain insight into the SecA-SecYEG interaction we used peptide arrays, thermodynamic quantitation, mutagenesis and functional assays. Our data reveal that: a. SecA binds with low...

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Autores principales: Karamanou, Spyridoula, Bariami, Vassiliki, Papanikou, Efrosyni, Kalodimos, Charalampos G., Economou, Anastassios
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603171/
https://ncbi.nlm.nih.gov/pubmed/18761620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06402.x
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