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A Chemical Genomics Study Identifies Snf1 as a Repressor of GCN4 Translation

The Saccharomyces cerevisiae Snf1 kinase plays a critical role in recalibrating cellular metabolism in response to glucose depletion. Hundreds of genes show changes in expression levels when the SNF1 gene is deleted. However, cells can adapt to the absence of a specific gene when grown in long term...

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Autors principals: Shirra, Margaret K., McCartney, Rhonda R., Zhang, Chao, Shokat, Kevan M., Schmidt, Martin C., Arndt, Karen M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602918/
https://ncbi.nlm.nih.gov/pubmed/18955495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805325200
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