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Activation of c-Src and Fyn Kinases by Protein-tyrosine Phosphatase RPTPα Is Substrate-specific and Compatible with Lipid Raft Localization

Src family tyrosine kinases (SFKs) function in multiple signaling pathways, raising the question of how appropriate regulation and substrate choice are achieved. SFK activity is modulated by several protein-tyrosine phosphatases, among which RPTPα and SHP2 are the best established. We studied how RP...

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Detalhes bibliográficos
Main Authors: Vacaresse, Nathalie, Møller, Bente, Danielsen, E. Michael, Okada, Masato, Sap, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602903/
https://ncbi.nlm.nih.gov/pubmed/18948260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807964200
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