Genetic basis of HDL variation in 129/SvImJ and C57BL/6J mice: importance of testing candidate genes in targeted mutant mice

To evaluate the effect of genetic background on high-density lipoprotein cholesterol (HDL) levels in Soat1(−/−) mice, we backcrossed sterol O-acyltransferase 1 (Soat1)(−/−) mice, originally reported to have elevated HDL levels, to C57BL/6 mice and constructed a congenic strain with only a small regi...

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Dades bibliogràfiques
Autors principals: Su, Zhiguang, Wang, Xiaosong, Tsaih, Shirng-Wern, Zhang, Aihong, Cox, Allison, Sheehan, Susan, Paigen, Beverly
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602865/
https://ncbi.nlm.nih.gov/pubmed/18772481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800411-JLR200
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