Synapsis and catalysis by activated Tn3 resolvase mutants

The serine recombinase Tn3 resolvase catalyses recombination between two 114 bp res sites, each of which contains binding sites for three resolvase dimers. We have analysed the in vitro properties of resolvase variants with ‘activating’ mutations, which can catalyse recombination at binding site I o...

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Bibliographic Details
Main Authors: Olorunniji, Femi J., He, Jiuya, Wenwieser, Sandra V.C.T., Boocock, Martin R., Stark, W. Marshall
Format: Artigo
Language:Inglês
Published: Oxford University Press 2008
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2602789/
https://ncbi.nlm.nih.gov/pubmed/19015124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn885
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