Role of interleukin-1 in the depression of liver drug metabolism by endotoxin.

Endotoxin-resistant C3H/HeJ mice were used to test the hypothesis that a macrophage product, possibly interleukin-1, might mediate the depression of liver cytochrome P-450-dependent drug metabolism in endotoxin-treated mice. Depression of liver drug metabolism by endotoxin was observed in normal mic...

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Hauptverfasser: Ghezzi, P, Saccardo, B, Villa, P, Rossi, V, Bianchi, M, Dinarello, C A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC260246/
https://ncbi.nlm.nih.gov/pubmed/3491050
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