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Endotoxin depresses hepatic cytochrome P450-mediated drug metabolism in women

Aims In men, the inflammatory response to intravenous endotoxin depresses apparent oral clearances of antipyrine, hexobarbitone, and theophylline. The aim of this study was to investigate whether there might be gender differences in the regulation of hepatic cytochromes P450. Methods Experiments wer...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Shedlofsky, S. I., Israel, B. C., Tosheva, R., Blouin, R. A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Wiley-Blackwell 1997
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042794/
https://ncbi.nlm.nih.gov/pubmed/9205823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.00603.x
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