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Rabbit antibodies to the cell wall polysaccharide of Streptococcus pneumoniae fail to protect mice from lethal challenge with encapsulated pneumococci.

A conjugate, composed of the cell wall polysaccharide (C polysaccharide) of Streptococcus pneumoniae and bovine serum albumin (BSA), was prepared with the bifunctional agent N-succinimidyl-3-(2-pyridyldithio)-propionate. Analysis with monoclonal antibodies provided evidence that the phosphocholine (...

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Detalles Bibliográficos
Publicado en:Infect Immun
Principais autores: Szu, S C, Schneerson, R, Robbins, J B
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1986
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC260182/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3095243/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.54.2.448-455.1986
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