Cutting Edge: K63-Linked Polyubiquitination of NEMO Modulates TLR Signaling and Inflammation In Vivo

Transcription factor NF-κB controls the expression of multiple genes involved in immunity and inflammation. The initial activation and duration of NF-κB signaling is regulated by posttranslational modifications to IκB kinase, which earmarks inhibitors of NF-κB for degradation. Prior studies suggest...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Ni, Chang-Yuan, Wu, Zhao-Hui, Florence, William C., Parekh, Vrajesh V., Arrate, Maria Pia, Pierce, Steven, Schweitzer, Brock, Van Kaer, Luc, Joyce, Sebastian, Miyamoto, Shigeki, Ballard, Dean W., Oltz, Eugene M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601684/
https://ncbi.nlm.nih.gov/pubmed/18490708
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi