Cutting Edge: K63-Linked Polyubiquitination of NEMO Modulates TLR Signaling and Inflammation In Vivo

Transcription factor NF-κB controls the expression of multiple genes involved in immunity and inflammation. The initial activation and duration of NF-κB signaling is regulated by posttranslational modifications to IκB kinase, which earmarks inhibitors of NF-κB for degradation. Prior studies suggest...

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Detalhes bibliográficos
Main Authors: Ni, Chang-Yuan, Wu, Zhao-Hui, Florence, William C., Parekh, Vrajesh V., Arrate, Maria Pia, Pierce, Steven, Schweitzer, Brock, Van Kaer, Luc, Joyce, Sebastian, Miyamoto, Shigeki, Ballard, Dean W., Oltz, Eugene M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2601684/
https://ncbi.nlm.nih.gov/pubmed/18490708
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