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A function for IL-7R for CD4(+)CD25(+) Foxp3(+) T regulatory cells
The IL-2/IL-2R interaction is important for development and peripheral homeostasis of T regulatory (T(reg)) cells. IL-2- and IL-2R-deficient mice are not completely devoid of Foxp3(+) cells, but rather lack population of mature CD4(+)CD25(+)Foxp3(high) T(reg) cells and contain few immature CD4(+)CD2...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2601574/ https://ncbi.nlm.nih.gov/pubmed/18566388 |
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