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The Polymorphism Frequency Spectrum of Finitely Many Sites Under Selection

The distribution of genetic polymorphisms in a population contains information about evolutionary processes. The Poisson random field (PRF) model uses the polymorphism frequency spectrum to infer the mutation rate and the strength of directional selection. The PRF model relies on an infinite-sites a...

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Detalhes bibliográficos
Main Authors: Desai, Michael M., Plotkin, Joshua B.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600950/
https://ncbi.nlm.nih.gov/pubmed/18854590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.087361
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