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Genome-wide structural mapping of protein interactions reveals differences in abundance-and expression-dependent evolutionary pressures
Genome-wide studies in Saccharomyces cerevisiae concluded that the dominant determinant of protein evolutionary rates is expression level, where highly-expressed proteins evolve most slowly. To determine how this constraint affects the evolution of protein interactions, we directly measure evolution...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2600897/ https://ncbi.nlm.nih.gov/pubmed/17997970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2007.09.010 |
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