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NF1 loss disrupts Schwann cell–axonal interactions: a novel role for semaphorin 4F
Neurofibromatosis type 1 (NF1) patients develop neurofibromas, tumors of Schwann cell origin, as a result of loss of the Ras-GAP neurofibromin. In normal nerves, Schwann cells are found tightly associated with axons, while loss of axonal contact is a frequent and important early event in neurofibrom...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2600763/ https://ncbi.nlm.nih.gov/pubmed/19056885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.490608 |
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