Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation

During early mouse development, the anterior visceral endoderm (AVE) secretes inhibitor and activator signals that are essential for establishing the anterior–posterior (AP) axis of the embryo and for restricting mesoderm formation to the posterior epiblast in the primitive streak (PS) region. Here...

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Bibliographic Details
Main Authors: Egea, Joaquim, Erlacher, Christian, Montanez, Eloi, Burtscher, Ingo, Yamagishi, Satoru, Heß, Martin, Hampel, Falko, Sanchez, Rodrigo, Rodriguez-Manzaneque, Maria Teresa, Bösl, Michael R., Fässler, Reinhard, Lickert, Heiko, Klein, Rüdiger
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2008
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600762/
https://ncbi.nlm.nih.gov/pubmed/19056886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.486708
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