Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation

During early mouse development, the anterior visceral endoderm (AVE) secretes inhibitor and activator signals that are essential for establishing the anterior–posterior (AP) axis of the embryo and for restricting mesoderm formation to the posterior epiblast in the primitive streak (PS) region. Here...

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Detalhes bibliográficos
Main Authors: Egea, Joaquim, Erlacher, Christian, Montanez, Eloi, Burtscher, Ingo, Yamagishi, Satoru, Heß, Martin, Hampel, Falko, Sanchez, Rodrigo, Rodriguez-Manzaneque, Maria Teresa, Bösl, Michael R., Fässler, Reinhard, Lickert, Heiko, Klein, Rüdiger
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600762/
https://ncbi.nlm.nih.gov/pubmed/19056886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.486708
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