Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation

During early mouse development, the anterior visceral endoderm (AVE) secretes inhibitor and activator signals that are essential for establishing the anterior–posterior (AP) axis of the embryo and for restricting mesoderm formation to the posterior epiblast in the primitive streak (PS) region. Here...

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Bibliographische Detailangaben
Hauptverfasser: Egea, Joaquim, Erlacher, Christian, Montanez, Eloi, Burtscher, Ingo, Yamagishi, Satoru, Heß, Martin, Hampel, Falko, Sanchez, Rodrigo, Rodriguez-Manzaneque, Maria Teresa, Bösl, Michael R., Fässler, Reinhard, Lickert, Heiko, Klein, Rüdiger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600762/
https://ncbi.nlm.nih.gov/pubmed/19056886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.486708
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